Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631484 | 0.83 | RAB9A (0.57) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL8628965 | 0.83 | LMNA (0.56) | NPSR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8630668 | 0.81 | WDR5 (0.55) | NPC1RAB9AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11547674 | 0.81 | ALDH1A1 (0.63) | ATF4NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL8629744 | 0.81 | KMT2A (0.56) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1255820 | 0.79 | ATF4 (0.63) | ATF4NPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8626932 | 0.78 | POLB (0.59) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11431811 | 0.78 | NPC1 (0.58) | ATF4NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL21004114 | 0.78 | L3MBTL1 (0.63) | ATF4NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL12693872 | 0.77 | KMT2A (0.61) | ATF4NPSR1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |