Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626932 | 0.95 | POLB (0.59) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL432126 | 0.86 | CYP19A1 (0.67) | ALDH1A1KMT2APOLBMEN1CYP19A1 | |
| SCHEMBL2836012 | 0.79 | POLB (0.63) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL14846355 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL7778609 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL8631484 | 0.74 | RAB9A (0.57) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL8628965 | 0.74 | LMNA (0.56) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8629515 | 0.74 | ATF4 (0.56) | ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3999404 | 0.73 | ALDH1A1 (0.76) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL11431170 | 0.73 | PLA2G4B (0.68) | ALDH1A1KMT2APOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |