SCHEMBL8630704

SCHEMBL8630704

Cc1ccccc1-c1nc(=O)cco1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.48
RAB9A P51151 7/20 0.48
SMN1; SMN2 Q16637 6/20 0.48
CASP3 P42574 3/20 0.48
SENP7 Q9BQF6 3/20 0.48
SENP6 Q9GZR1 3/20 0.48
SENP8 Q96LD8 2/20 0.48
NOTUM Q6P988 1/20 0.47
ELANE P08246 1/20 0.46
ALDH1A1 P00352 4/20 0.42
HPGD P15428 2/20 0.42
TSHR P16473 2/20 0.42
IKBKB O14920 1/20 0.42
GAA P10253 2/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9347721 0.80 NPC1 (0.42) NPC1RAB9ASMN1; SMN2ALDH1A1HPGD
SCHEMBL6244930 0.79 GPR55 (0.47) NPC1RAB9ASMN1; SMN2ELANEALDH1A1
SCHEMBL9616811 0.77 ENPP3 (0.58) NPC1RAB9ASMN1; SMN2CASP3SENP7
SCHEMBL724756 0.76 CASP3 (0.41) SMN1; SMN2CASP3SENP7SENP6SENP8
SCHEMBL9347252 0.73 PTGS2 (0.41) NPC1RAB9ASMN1; SMN2CASP3SENP7
SCHEMBL130959 0.73 ALDH1A1 (0.44) NPC1RAB9ASMN1; SMN2NOTUMELANE
SCHEMBL17068993 0.72 RAB9A (0.53) NPC1RAB9ASMN1; SMN2CASP3SENP7
SCHEMBL3031254 0.72 RAB9A (0.53) NPC1RAB9ASMN1; SMN2CASP3SENP7
SCHEMBL9616767 0.70 PIP4K2C (0.47) ENPP3
SCHEMBL7744187 0.68 HDAC1 (0.49) NPC1RAB9ASMN1; SMN2CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695289-B1 HYDROXAMIC ACIDS AND HYDROXAMIC ACID ETHERS AND THEIR USE AS COMPLEXING AGENTS BASF AG (DE) 1998-07-01 EP disclosed
EP-0695289-A1 HYDROXAMIC ACIDS AND HYDROXAMIC ACID ETHERS AND THEIR USE AS COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-07 EP disclosed
WO-1994024096-A1 HYDROXAMIC ACIDS AND HYDROXAMIC ACID ETHERS AND THEIR USE AS COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed
EP-0502013-A1 USE OF HETEROCYCLIC COMPOUNDS AS BLEACH ACTIVATORS OR OPTICAL LIGHTENERS IN WASHING AND CLEANING AGENTS. BASF AG (DE) 1992-09-09 EP disclosed
EP-0456109-A2 Process for producing granular bleaching activator composition BASF Aktiengesellschaft (DE) 1991-11-13 EP disclosed