Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635339 | 0.87 | MTNR1A (0.42) | CYP2C9LMNACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8635629 | 0.86 | FLT1 (0.36) | KCNJ6KCNJ5KCNJ3TP53RXRA | |
| SCHEMBL8632126 | 0.86 | TUBB4A (0.37) | KEAP1NFE2L2TUBB4ATUBBTUBA3C | |
| SCHEMBL8635192 | 0.85 | RXRA (0.35) | KCNJ6KCNJ5KCNJ3LMNAKMT2A | |
| SCHEMBL8635012 | 0.85 | NSD2 (0.36) | RXRARXRBRXRG | |
| SCHEMBL7764019 | 0.83 | SLC9A1 (0.57) | — | |
| SCHEMBL8635329 | 0.83 | SLC9A1 (0.35) | LMNARXRARXRBRXRGALDH1A1 | |
| SCHEMBL8633950 | 0.82 | SIRT2 (0.35) | RXRARXRBRXRGPDK1PDK2 | |
| SCHEMBL8635732 | 0.82 | KCNJ6 (0.38) | KCNJ6KCNJ3 | |
| SCHEMBL8638262 | 0.80 | HPGD (0.39) | LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |