Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.58 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495305 | 0.82 | DRD2 (0.65) | DRD2DRD3LMNAL3MBTL1HTR3E | |
| SCHEMBL10660538 | 0.81 | DRD2 (0.63) | DRD2DRD3LMNAL3MBTL1HTR3E | |
| SCHEMBL9035759 | 0.79 | ADRA1A (0.80) | DRD2DRD3HTR1AADRA1A | |
| SCHEMBL327835 | 0.78 | DRD2 (1.00) | DRD2DRD3LMNAHTR3EHTR3B | |
| SCHEMBL30407688 | 0.77 | DRD2 (0.72) | DRD2DRD3LMNAL3MBTL1HTR3E | |
| SCHEMBL3165674 | 0.77 | DRD2 (0.72) | DRD2DRD3LMNAHTR3EHTR3B | |
| SCHEMBL8634780 | 0.77 | SMN1; SMN2 (0.48) | DRD2DRD3LMNAL3MBTL1SLC2A1 | |
| SCHEMBL15819139 | 0.77 | NTSR1 (0.50) | DRD2DRD3LMNAL3MBTL1SLC2A1 | |
| Phenylpiperazine SCHEMBL3440604 | 0.76 | HTR3A (0.84) | DRD2DRD3LMNAHTR3EHTR3B | |
| SCHEMBL217093 | 0.76 | DRD2 (0.66) | DRD2DRD3LMNAL3MBTL1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |