SCHEMBL8635276

SCHEMBL8635276

CCC(C)c1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
TSHR P16473 1/20 0.36
AR P10275 4/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CASP1 P29466 1/20 0.33
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.32
PDE3B Q13370 2/20 0.32
PDE3A Q14432 2/20 0.32
KCNH2 Q12809 1/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP17A1 P05093 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635950 0.92 PPARG (0.34) ARFFAR1FFAR4HTTPDE3B
SCHEMBL8634067 0.89 ALDH1A1 (0.36) ALDH1A1TSHRARFFAR1CASP1
SCHEMBL8634403 0.85 FFAR4 (0.43) ARFFAR4HTT
SCHEMBL8635048 0.85 MAPT (0.44) ALDH1A1ARKMT2AHTTPDE3B
SCHEMBL8633073 0.84 L3MBTL1 (0.39) ALDH1A1ARMEN1KMT2AHTT
SCHEMBL8635558 0.83 LTA4H (0.43) ARHTTPDE3BPDE3AMAPT
SCHEMBL8635519 0.83 LTA4H (0.43) HTT
SCHEMBL8636474 0.83 RXRA (0.38) ARFFAR1KCNH2MAPTLMNA
SCHEMBL8634174 0.83 AR (0.39) ARFFAR4
SCHEMBL8632518 0.82 MAPT (0.39) ALDH1A1ARHTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed