SCHEMBL8635945

SCHEMBL8635945

CCCCCc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.43
PSEN1 P49768 2/20 0.38
ALOX5 P09917 2/20 0.38
PPARG P37231 2/20 0.38
THRB P10828 2/20 0.37
PTGES O14684 1/20 0.36
THRA P10827 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634546 0.89 S1PR1 (0.43) S1PR1PSEN1ALOX5PPARGTHRB
SCHEMBL8635519 0.89 LTA4H (0.43) S1PR1PSEN1ALOX5PPARGTHRB
SCHEMBL8635016 0.85 S1PR1 (0.37) S1PR1PSEN1ALOX5PPARGTHRB
SCHEMBL8635558 0.84 LTA4H (0.43) S1PR1ALOX5PPARGPTGES
SCHEMBL8635048 0.84 MAPT (0.44)
SCHEMBL8633073 0.83 L3MBTL1 (0.39)
SCHEMBL8634174 0.82 AR (0.39) PSEN1ALOX5PPARG
SCHEMBL8636474 0.82 RXRA (0.38) PSEN1ALOX5PPARGTHRB
SCHEMBL8632518 0.81 MAPT (0.39) PPARG
SCHEMBL8633864 0.81 MAOB (0.36) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed