SCHEMBL8635558

SCHEMBL8635558

CCCOc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.43
MAPK8 P45983 1/20 0.39
MAPK10 P53779 1/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
PTPN7 P35236 1/20 0.38
DUSP3 P51452 1/20 0.38
SCN8A Q9UQD0 1/20 0.37
SCN10A Q9Y5Y9 1/20 0.37
HTT P42858 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
PPARA Q07869 6/20 0.35
PPARG P37231 4/20 0.35
PPARD Q03181 3/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635519 0.95 LTA4H (0.43) LTA4HHTTPPARAPPARGPPARD
SCHEMBL8635048 0.91 MAPT (0.44) LTA4HMAPK8MAPK10PDE3BPDE3A
SCHEMBL8632120 0.88 LTA4H (0.43) LTA4HMAPK8MAPK10PDE3BPDE3A
SCHEMBL8636074 0.87 KDM4E (0.37) SCN8ASCN10AHTTPPARAMAPT
SCHEMBL8633073 0.87 L3MBTL1 (0.39) MAPK8MAPK10HTTLMNAMAPT
SCHEMBL8636474 0.85 RXRA (0.38) LTA4HPPARGPPARDLMNAMAPT
SCHEMBL8634174 0.85 AR (0.39) PPARAPPARGPPARDARALOX5
SCHEMBL8632518 0.85 MAPT (0.39) HTTPPARGPPARDLMNAMAPT
SCHEMBL8635945 0.84 S1PR1 (0.43) PPARGS1PR1PTGESALOX5
SCHEMBL8633864 0.84 MAOB (0.36) MAPK8MAPK10HTTPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed