Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635768 | 0.88 | ALDH1A1 (0.37) | ALDH1A1HTTLMNAHDAC6POLB | |
| SCHEMBL7766577 | 0.86 | SLC9A1 (0.42) | — | |
| SCHEMBL8634234 | 0.84 | MEN1 (0.36) | POLB | |
| SCHEMBL8635259 | 0.83 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8635203 | 0.82 | HSP90AA1 (0.35) | ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8634221 | 0.82 | SIRT2 (0.34) | ALDH1A1LMNAPGR | |
| SCHEMBL8633199 | 0.82 | PER2 (0.36) | — | |
| SCHEMBL8634165 | 0.81 | ESR1 (0.39) | ALDH1A1 | |
| SCHEMBL8633152 | 0.80 | RORC (0.38) | HDAC6 | |
| SCHEMBL8631189 | 0.78 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |