Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636273 | 0.88 | ALDH1A1 (0.36) | ALDH1A1HTTLMNAHDAC6POLB | |
| SCHEMBL7761277 | 0.84 | SLC9A1 (0.55) | SLC9A1 | |
| SCHEMBL8633203 | 0.83 | MEN1 (0.35) | POLBSLC9A1 | |
| SCHEMBL8635496 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBSLC9A1 | |
| SCHEMBL8635012 | 0.81 | NSD2 (0.36) | POLBSLC9A1 | |
| SCHEMBL8633950 | 0.81 | SIRT2 (0.35) | SLC9A1 | |
| SCHEMBL8638262 | 0.81 | HPGD (0.39) | ALDH1A1LMNAPOLB | |
| SCHEMBL8635870 | 0.80 | KCNJ6 (0.39) | — | |
| SCHEMBL8632865 | 0.80 | RORC (0.36) | HDAC6 | |
| SCHEMBL8633215 | 0.76 | L3MBTL1 (0.42) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |