Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KLRK1 | P26718 | 4/20 | 0.36 |
| ▸ | MICA | Q29983 | 4/20 | 0.36 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | APOB | P04114 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637431 | 0.85 | LGMN (0.37) | PPARGPPARA | |
| SCHEMBL8633152 | 0.83 | RORC (0.38) | — | |
| SCHEMBL8635259 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL8634234 | 0.79 | MEN1 (0.36) | POLB | |
| SCHEMBL8635203 | 0.78 | HSP90AA1 (0.35) | POLB | |
| SCHEMBL8634165 | 0.76 | ESR1 (0.39) | — | |
| SCHEMBL8636273 | 0.75 | ALDH1A1 (0.36) | POLB | |
| SCHEMBL8635757 | 0.73 | SMN1; SMN2 (0.31) | CYP2C9 | |
| SCHEMBL8636231 | 0.73 | MCL1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8631189 | 0.73 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |