Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884797 | 0.77 | ALDH1A1 (0.40) | HTR7BRD4MAPTNOTUMUSP2 | |
| SCHEMBL8347291 | 0.74 | PDE4A (0.46) | CD274MAPT | |
| SCHEMBL8350829 | 0.73 | AHR (0.48) | ADRB1PNMTMAPTASIC3NOTUM | |
| SCHEMBL8638170 | 0.73 | MLNR (0.39) | PNMTASIC3NOTUM | |
| SCHEMBL14956908 | 0.70 | QDPR (0.60) | HTR7 | |
| SCHEMBL8638141 | 0.69 | SIGMAR1 (0.52) | HTR7PNMTASIC3 | |
| SCHEMBL8635851 | 0.69 | HTR2A (0.42) | HTR7 | |
| SCHEMBL8640742 | 0.69 | PTGS2 (0.44) | CD274 | |
| SCHEMBL8638940 | 0.69 | NISCH (0.43) | HTR7ADRB1CD274 | |
| SCHEMBL27676378 | 0.69 | PRCP (0.48) | HTR7PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |