Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889342 | 0.93 | MAOA (0.54) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL4886794 | 0.91 | SIGMAR1 (0.54) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL4892662 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL4896504 | 0.83 | HDAC3 (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL3334933 | 0.82 | SIGMAR1 (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11774828 | 0.79 | HDAC3 (0.47) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11774835 | 0.79 | HDAC3 (0.47) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL430012 | 0.78 | SIGMAR1 (0.54) | SIGMAR1MAOAMAOBADRA1ASLC6A3 | |
| SCHEMBL364434 | 0.78 | SIGMAR1 (0.48) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL3591598 | 0.78 | HDAC3 (0.50) | ALOX15SIGMAR1TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077844-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | L'OREAL (FR) | 2012-03-29 | — | — | US | disclosed |
| US-20100048624-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | L'OREAL (FR) | 2010-02-25 | — | — | US | disclosed |
| US-7629359-B2 | Use of piperidine derivatives as dermo-decontracting agents | L'OREAL (FR) | 2009-12-08 | — | — | US | disclosed |
| EP-1765281-B1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | OREAL (FR) | 2008-08-27 | — | — | EP | disclosed |
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC | 2008-08-14 | — | — | US | disclosed |
| US-20070259915-A1 | Use of Piperidine Derivatives as Dermo-Decontracting Agents | L'OREAL (FR) | 2007-11-08 | — | — | US | disclosed |
| EP-1765281-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | L'OREAL (FR) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006003030-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | L'OREAL (FR) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077844-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | PLOD3, CUTA, DSTN | ALDH1A1 429/4885HPGD 703/4885ALOX15 343/4885 |
| US-20070259915-A1 | Use of Piperidine Derivatives as Dermo-Decontracting Agents | CUTA, PLOD3, PLIN5 | ALDH1A1 443/4885HPGD 728/4885ALOX15 341/4885 |
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFKP, PF4, P2RY4 | ALDH1A1 1204/4885HPGD 1749/4885ALOX15 3326/4885 |
| US-20100048624-A1 | USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS | PLOD3, CUTA, DSTN | ALDH1A1 429/4885HPGD 703/4885ALOX15 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.