Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | TPI1 | P60174 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | MVD | P53602 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322571 | 0.82 | PEPD (0.39) | PEPDTPI1PGK1PGK2PGD | |
| SCHEMBL6150390 | 0.81 | TPI1 (0.46) | PEPDTPI1LPAR3LPAR2PGK1 | |
| SCHEMBL12394924 | 0.79 | TPI1 (0.35) | TPI1LPAR3LPAR2LPAR1BTN3A1 | |
| SCHEMBL12394925 | 0.79 | TPI1 (0.35) | TPI1LPAR3LPAR2LPAR1BTN3A1 | |
| SCHEMBL632959 | 0.78 | PEPD (0.34) | PEPDPGK1PGK2 | |
| SCHEMBL3286421 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL830037 | 0.78 | PGK1 (0.42) | PEPDTPI1LPAR3LPAR2LPAR1 | |
| SCHEMBL1831267 | 0.78 | THRB (0.39) | TPI1LPAR3LPAR2LPAR1 | |
| Itaconate SCHEMBL9419182 | 0.76 | ALOX15 (0.41) | PEPDLPAR3LPAR2LPAR1MVD | |
| SCHEMBL1831246 | 0.76 | THRB (0.38) | LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575276-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2013-11-05 | — | — | US | claimed |
| US-20120078296-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-03-29 | — | — | US | claimed |
| US-8030413-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2011-10-04 | — | — | US | claimed |
| US-7622533-B2 | Biomimetic compounds and synthetic methods therefor | NERITES CORPORATION (US) | 2009-11-24 | — | — | US | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| US-20090076241-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION | 2009-03-19 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| EP-1548021-B1 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY DETREY GMBH (DE) | 2007-03-21 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
| WO-2005063778-A1 | ONE-PART SELF-ETCHING, SELF-PRIMING DENTAL ADHESIVE COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | PEPD 4822/4885TPI1 3784/4885LPAR3 675/4885 |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | PEPD 1469/4885TPI1 1446/4885LPAR3 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.