Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673227 | 0.82 | LMNA (0.44) | LMNAMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL9066544 | 0.82 | CES1 (0.53) | CES1LMNAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2799654 | 0.78 | DRD2 (0.51) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8673491 | 0.77 | ALDH1A1 (0.48) | LMNAMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL25638950 | 0.74 | L3MBTL1 (0.49) | LMNAMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL12005279 | 0.72 | MAPT (0.42) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8673363 | 0.71 | LMNA (0.41) | LMNAMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL10299607 | 0.69 | ALDH1A1 (0.48) | LMNAMAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL6245392 | 0.69 | ABCB1 (0.49) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL7594346 | 0.69 | CES1 (0.50) | CES1LMNAKMT2AHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744512-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-04-28 | — | — | US | claimed |
| US-5837746-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |