Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727935 | 0.76 | CA5A (0.46) | CA5ACA5BCA2 | |
| SCHEMBL800271 | 0.76 | KDM4E (0.46) | KDM4ECYP3A4CA2 | |
| Lithium SCHEMBL30522213 | 0.72 | CA5A (0.42) | CA5ACA5BCA2 | |
| Water SCHEMBL6822518 | 0.72 | CA5A (0.42) | CA5ACA5BCA2 | |
| SCHEMBL11969893 | 0.72 | CA5A (0.42) | CA5ACA5BCA2 | |
| SCHEMBL29044711 | 0.72 | CA5A (0.42) | CA5ACA5BCA2 | |
| SCHEMBL10626545 | 0.69 | ALDH1A1 (0.32) | KDM4ECYP3A4CA5ACA5BCA2 | |
| SCHEMBL15109974 | 0.66 | — | — | |
| SCHEMBL25599 | 0.66 | CA2 (0.58) | KDM4ECYP3A4CA5ACA5BCA2 | |
| SCHEMBL105 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618903-B1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEM CO (US) | 2016-01-27 | — | — | EP | claimed |
| EP-2831029-A1 | HYDROCARBOXYLATION OF METHYLENE DIPROPIONATE IN THE PRESENCE OF A PROPIONIC ACID AND A HOMOGENEOUS CATALYST | Eastman Chemical Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831026-A1 | HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND A HOMOGENEOUS CATALYST | Eastman Chemical Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831040-A1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | Eastman Chemical Company (US) | 2015-02-04 | — | — | EP | claimed |
| US-8927766-B2 | Hydrocarboxylation of methylene dipropionate in the presence of a propionic acid and a homogeneous catalyst | EASTMAN CHEMICAL COMPANY (US) | 2015-01-06 | — | — | US | claimed |
| US-8785686-B2 | Process for recovering and recycling an acid catalyst | EASTMAN CHEMICAL COMPANY (US) | 2014-07-22 | — | — | US | claimed |
| US-8765999-B2 | Hydrocarboxylation of formaldehyde in the presence of a higher order carboxylic acid and a homogeneous catalyst | EASTMAN CHEMICAL COMPANY (US) | 2014-07-01 | — | — | US | claimed |
| US-8709376-B2 | Process for recovering and recycling an acid catalyst | EASTMAN CHEMICAL COMPANY (US) | 2014-04-29 | — | — | US | claimed |
| US-20130261329-A1 | HYDROCARBOXYLATION OF METHYLENE DIPROPIONATE IN THE PRESENCE OF A PROPIONIC ACID AND A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2013-10-03 | — | — | US | claimed |
| US-20130261328-A1 | HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2013-10-03 | — | — | US | claimed |
| WO-2013148497-A1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2013-10-03 | — | — | WO | claimed |
| WO-2013148513-A1 | HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2013-10-03 | — | — | WO | claimed |
| WO-2013148483-A1 | HYDROCARBOXYLATION OF METHYLENE DIPROPIONATE IN THE PRESENCE OF A PROPIONIC ACID AND A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2013-10-03 | — | — | WO | claimed |
| EP-2618903-A2 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | Eastman Chemical Company (US) | 2013-07-31 | — | — | EP | claimed |
| US-20120215027-A1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2012-08-23 | — | — | US | claimed |
| US-20120078010-A1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2012-03-29 | — | — | US | claimed |
| WO-2012040007-A2 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2012-03-29 | — | — | WO | claimed |
| EP-2618903-B1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEM CO (US) | 2016-01-27 | — | — | EP | disclosed |
| US-20120078010-A1 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2012040007-A2 | PROCESS FOR RECOVERING AND RECYCLING AN ACID CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261328-A1 | HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND A HOMOGENEOUS CATALYST | GRHPR, HAO2, HPD | KDM4E 1119/4885CYP3A4 115/4885CA5A 465/4885 |
| US-20130261329-A1 | HYDROCARBOXYLATION OF METHYLENE DIPROPIONATE IN THE PRESENCE OF A PROPIONIC ACID AND A HOMOGENEOUS CATALYST | GRHPR, HPD, PGD | KDM4E 1249/4885CYP3A4 94/4885CA5A 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.