Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ACR | P10323 | 2/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850236 | 0.81 | RARB (0.45) | POLBKMT2AMAPTLMNATSHR | |
| SCHEMBL9850207 | 0.77 | RARB (0.47) | POLBKMT2AMAPTLMNATSHR | |
| SCHEMBL9850181 | 0.70 | RXRA (0.46) | KMT2AMEN1CYP26A1RARBRARG | |
| SCHEMBL8460713 | 0.70 | RARA (0.58) | KMT2AMAPTLMNAMEN1CYP3A4 | |
| SCHEMBL9850280 | 0.69 | RXRA (0.41) | POLBKMT2AMAPTLMNATSHR | |
| SCHEMBL9850132 | 0.68 | RARA (0.51) | KMT2AMAPTLMNATSHRRAB9A | |
| SCHEMBL16357038 | 0.68 | ACR (0.56) | POLBKMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9850128 | 0.68 | COXFA4 (0.47) | POLBKMT2AMAPTLMNATSHR | |
| SCHEMBL9850140 | 0.68 | MAPT (0.41) | POLBKMT2AMAPTLMNATSHR | |
| SCHEMBL9850125 | 0.67 | RARB (0.55) | POLBKMT2AMEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007716-A2 | HETEROAROTINOIDS-ANTICANCER AGENTS WITH RECEPTOR SPECIFICITY AND TGASE ACTIVITY | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 1998-02-26 | — | — | WO | disclosed |