Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 9/20 | 0.35 |
| ▸ | HTR7 | P34969 | 9/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 5/20 | 0.35 |
| ▸ | WNT3 | P56703 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665590 | 0.95 | CTSB (0.34) | CCR3HTR1AHTR7SFRP1WNT3 | |
| SCHEMBL8485545 | 0.86 | NPSR1 (0.40) | CCR3 | |
| SCHEMBL8713186 | 0.84 | DRD2 (0.36) | DRD2 | |
| SCHEMBL8484461 | 0.84 | NPSR1 (0.39) | CCR3 | |
| SCHEMBL8665883 | 0.83 | NPSR1 (0.37) | CCR3DRD2 | |
| SCHEMBL8664874 | 0.81 | DRD2 (0.33) | CCR3DRD2 | |
| SCHEMBL8717987 | 0.81 | CCR3 (0.44) | CCR3HTR1AHTR7DRD2HTT | |
| SCHEMBL8666099 | 0.81 | NPSR1 (0.36) | CCR3DRD2 | |
| SCHEMBL8648481 | 0.80 | CCR3 (0.39) | CCR3HTR1AHTR7DRD2 | |
| SCHEMBL8651970 | 0.80 | SLC6A12 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |