Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718953 | 0.90 | STAT3 (0.41) | ADRB2STAT3CYP19A1SIGMAR1CA2 | |
| SCHEMBL8713354 | 0.88 | ALOX15 (0.40) | ADRB2STAT3CYP19A1CA2MEN1 | |
| SCHEMBL8720032 | 0.88 | KDM4E (0.40) | ADRB2ADRB1ADRB3STAT3CYP19A1 | |
| SCHEMBL8719246 | 0.87 | ATM (0.40) | ADRB2ADRB1ADRB3STAT3CYP19A1 | |
| SCHEMBL8713860 | 0.84 | HTT (0.47) | ADRB2STAT3CYP19A1SIGMAR1CA2 | |
| SCHEMBL8718108 | 0.83 | ABCB1 (0.46) | LMNAMEN1KMT2AKDM4EATM | |
| SCHEMBL8716634 | 0.81 | NR3C1 (0.38) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8713152 | 0.81 | RAB9A (0.39) | STAT3CYP19A1LMNAMEN1KMT2A | |
| SCHEMBL8714103 | 0.81 | EPHX2 (0.41) | ADRB2ADRB1ADRB3STAT3CYP19A1 | |
| SCHEMBL8716946 | 0.80 | ADRB2 (0.41) | ADRB2ADRB1ADRB3STAT3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |