Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.37 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839797 | 0.83 | LMNA (0.57) | LMNACYP3A4MAPTKDM4EERN1 | |
| Sulfuric Acid SCHEMBL28806456 | 0.80 | LMNA (0.77) | LMNACYP3A4MAPTKDM4EERN1 | |
| Sulfuric Acid SCHEMBL3271974 | 0.80 | LMNA (0.77) | LMNACYP3A4MAPTKDM4EERN1 | |
| Sulfuric Acid SCHEMBL7488838 | 0.80 | LMNA (0.77) | LMNACYP3A4MAPTKDM4EERN1 | |
| Water SCHEMBL29026640 | 0.76 | LMNA (0.45) | LMNACYP3A4MAPTKDM4EERN1 | |
| SCHEMBL8811771 | 0.75 | KDM4E (0.55) | LMNACYP3A4MAPTKDM4EERN1 | |
| Sulfuric Acid SCHEMBL11132378 | 0.74 | LMNA (0.79) | LMNACYP3A4MAPTKDM4EERN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL6799589 | 0.74 | LMNA (0.66) | LMNACYP3A4MAPTKDM4EERN1 | |
| SCHEMBL11241351 | 0.73 | LMNA (0.61) | LMNACYP3A4MAPTKDM4EERN1 | |
| SCHEMBL8313 | 0.73 | LMNA (1.00) | LMNACYP3A4MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759714-A | REVERSIBLY ABSORBING AND REKEASING LITHIUM | FUJI PHOTO FILM CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0785586-A1 | Non-aqueous-electrolyte secondary battery | FUJI PHOTO FILM CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |