SCHEMBL8716552

SCHEMBL8716552

C=CCN(CC=C)C(C)(C)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10873481 0.81 ALDH1A1 (0.30) ALDH1A1DPP4
SCHEMBL2049203 0.78 ALDH1A1 (0.31) ALDH1A1DPP4
SCHEMBL9718368 0.77 MAPT (0.32)
SCHEMBL5613538 0.77
Hydrochloric Acid SCHEMBL5270865 0.74
SCHEMBL9254464 0.74
SCHEMBL9283375 0.71
SCHEMBL5955613 0.71 RAB9A (0.36) ALDH1A1DPP4
SCHEMBL22267414 0.70
SCHEMBL3861415 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9993500-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2018-06-12 US claimed
US-9205107-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2015-12-08 US claimed
US-11992501-B2 Compositions for and methods of treating acid-base disorders RENOSIS, INC. (US) 2024-05-28 US disclosed
US-11986490-B2 Compositions for and method of treating acid-base disorders RENOSIS, INC. (US) 2024-05-21 US disclosed
US-20230405043-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2023-12-21 US disclosed
US-11738041-B2 Proton-binding polymers for oral administration RENOSIS, INC. (US) 2023-08-29 US disclosed
US-20230031665-A1 COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2023-02-02 US disclosed
US-11311571-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2022-04-26 US disclosed
US-11197887-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2021-12-14 US disclosed
US-20210347925-A1 CROSSLINKED POLY(ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS RENIBUS THERAPEUTICS, INC. 2021-11-11 US disclosed
US-20210187011-A1 METHOD OF TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2021-06-24 US disclosed
US-9925214-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2018-03-27 US disclosed
EP-3287133-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION Tricida Inc. (US) 2018-02-28 EP disclosed
US-20180021370-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2018-01-25 US disclosed
US-20180015121-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2018-01-18 US disclosed
EP-3003327-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2017-08-09 EP disclosed
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2016-03-17 US disclosed
US-9205107-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2015-12-08 US disclosed
US-20150056451-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2015-02-26 US disclosed
US-5783535-A MIXTURES CONTAINING CONTROLLED AMOUNTS OF AMIDOETHER CARBOXYLIC ACIDS OR SALTS, AMIDOETHERS, GLYCERINE DERIVATIVES AND CONDITIONERS, FOR SHAMPOO, SKIN CLEANSING FOAM OR DISHWASHING DETERGENT KAO CORPORATION (JP) 1998-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992501-B2 Compositions for and methods of treating acid-base disorders SLC10A2, SLC10A1, SLC26A3 ALDH1A1 1554/4885DPP4 2350/4885
US-20150056451-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-20210187011-A1 METHOD OF TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, SI ALDH1A1 736/4885DPP4 1518/4885
US-20180021370-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-20210347925-A1 CROSSLINKED POLY(ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS PARG, PARN, AAAS ALDH1A1 779/4885DPP4 2649/4885
US-11738041-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-20230031665-A1 COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, GLS ALDH1A1 773/4885DPP4 2545/4885
US-20230405043-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-11986490-B2 Compositions for and method of treating acid-base disorders SLC10A2, SLC10A1, GLS ALDH1A1 773/4885DPP4 2545/4885
US-20180015121-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-11311571-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885
US-11197887-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 ALDH1A1 3400/4885DPP4 3580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.