Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907253 | 0.93 | GAA (0.40) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL8726598 | 0.76 | ALDH1A1 (0.33) | HSP90AA1NPSR1TDP1AKT1ALDH1A1 | |
| SCHEMBL25752898 | 0.74 | RAB9A (0.50) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL7908261 | 0.73 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL31165993 | 0.73 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL2058148 | 0.72 | HCAR3 (0.54) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL24660418 | 0.71 | NNMT (0.55) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL15758463 | 0.71 | RAB9A (0.46) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL27938545 | 0.70 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL13609853 | 0.70 | MGLL (0.48) | GAAHSP90AA1NPSR1TDP1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |