Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393916 | 0.79 | CA4 (0.46) | CA4 | |
| D-Glutamate SCHEMBL7568438 | 0.78 | GRM8 (0.37) | LMNA | |
| SCHEMBL3219620 | 0.78 | CA4 (0.44) | CA4 | |
| SCHEMBL7094704 | 0.77 | CA4 (0.40) | CA4 | |
| SCHEMBL149815 | 0.76 | ALDH1A1 (0.48) | CA4LMNAALDH1A1 | |
| SCHEMBL29234711 | 0.76 | CA4 (0.55) | CA4ALDH1A1 | |
| SCHEMBL8442297 | 0.76 | CA4 (0.46) | CA4 | |
| Water SCHEMBL7558083 | 0.75 | ALDH1A1 (0.47) | CA4LMNAALDH1A1 | |
| SCHEMBL1938661 | 0.75 | ALDH1A1 (0.47) | CA4LMNAALDH1A1 | |
| SCHEMBL2793489 | 0.75 | TDP1 (0.44) | CA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619313-B1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | DA YU ENTPR L L C (US) | 2021-11-10 | — | — | EP | disclosed |
| US-10119159-B2 | Method of recombinant macromolecular production | DA YU ENTERPRISES, L.L.C. (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180112246-A1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | DA YU ENTERPRISES, LLC | 2018-04-26 | — | — | US | disclosed |
| US-9856501-B2 | Method of recombinant macromolecular production | DA YU ENTERPRISES, L.L.C. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160244797-A1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | DA YU ENTERPRISES, L.L.C. | 2016-08-25 | — | — | US | disclosed |
| US-9267164-B2 | Method of recombinant macromolecular production | DA YU ENTERPRISES, L.L.C. (US) | 2016-02-23 | — | — | US | disclosed |
| EP-2619313-A1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | Da Yu Enterprises, L.L.C. (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20130183685-A1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | DA YU ENTERPRISES, L.L.C. (US) | 2013-07-18 | — | — | US | disclosed |
| WO-2012040550-A1 | METHOD OF RECOMBINANT MACROMOLECULAR PRODUCTION | DA YU ENTERPRISES, L.L.C. (US) | 2012-03-29 | — | — | WO | disclosed |