Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.50 |
| ▸ | CES1 | P23141 | 10/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671430 | 1.00 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL455070 | 0.87 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL457602 | 0.87 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5846740 | 0.80 | FAAH (0.44) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL540827 | 0.79 | FAAH (0.55) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5533296 | 0.79 | FAAH (0.55) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2556207 | 0.77 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28875 | 0.77 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL540430 | 0.76 | FAAH (0.41) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5929269 | 0.76 | FAAH (0.41) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060034792-A1 | Cosmetic composition based on a cationic surfactant, an amino silicone or vinyl silicone, a fatty alcohol and a propellant | L'OREAL (FR) | 2006-02-16 | — | — | US | claimed |
| US-8808400-B2 | Dyeing or lightening process using a composition rich in fatty substances comprising an alcohol having at least 20 carbons, compositions and device | L'OREAL (FR) | 2014-08-19 | — | — | US | disclosed |
| US-8802066-B2 | Cosmetic composition comprising a particular zinc salt and an amino silicone | L'OREAL (FR) | 2014-08-12 | — | — | US | disclosed |
| US-8784506-B2 | Dye composition having a low content of ammonia | L'OREAL (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20140053345-A1 | DYEING OR LIGHTENING PROCESS USING A COMPOSITION RICH IN FATTY SUBSTANCES COMPRISING AN ALCOHOL HAVING AT LEAST 20 CARBONS, COMPOSITIONS AND DEVICE | L'OREAL (FR) | 2014-02-27 | — | — | US | disclosed |
| US-20130340783-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR ZINC SALT AND AN AMINO SILICONE | L'OREAL (FR) | 2013-12-26 | — | — | US | disclosed |
| EP-2663368-A2 | DYEING OR LIGHTENING PROCESS USING A COMPOSITION RICH IN FATTY SUBSTANCES COMPRISING AN ALCOHOL HAVING AT LEAST 20 CARBONS, COMPOSITIONS AND DEVICE | L'Oréal (FR) | 2013-11-20 | — | — | EP | disclosed |
| US-20130298934-A1 | DYE COMPOSITION HAVING A LOW CONTENT OF AMMONIA | L'OREAL (FR) | 2013-11-14 | — | — | US | disclosed |
| EP-2654676-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR ZINC SALT AND AN AMINO SILICONE | L'Oréal (FR) | 2013-10-30 | — | — | EP | disclosed |
| EP-2645984-A1 | COSMETIC COMPOSITION CONTAINING A NON-AMINO SILICONE, A LIQUID FATTY ESTER AND AN AMINO SILICONE, PROCESS AND USE | L'Oréal (FR) | 2013-10-09 | — | — | EP | disclosed |
| EP-2635250-A1 | DYE COMPOSITION HAVING A LOW CONTENT OF AMMONIA | L'Oréal (FR) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012095397-A2 | DYEING OR LIGHTENING PROCESS USING A COMPOSITION RICH IN FATTY SUBSTANCES COMPRISING AN ALCOHOL HAVING AT LEAST 20 CARBONS, COMPOSITIONS AND DEVICE | L'OREAL (FR) | 2012-07-19 | — | — | WO | disclosed |
| WO-2012084903-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR ZINC SALT AND AN AMINO SILICONE | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084867-A1 | COSMETIC COMPOSITION COMPRISING A ZINC SALT, A CATIONIC POLYMER AND A PROPELLANT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084901-A1 | COSMETIC COMPOSITION COMPRISING A ZINC SALT AND A SOLID FATTY ESTER | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012072765-A1 | COSMETIC COMPOSITION CONTAINING A NON-AMINO SILICONE, A LIQUID FATTY ESTER AND AN AMINO SILICONE, PROCESS AND USE | L'OREAL (FR) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012059410-A1 | DYE COMPOSITION HAVING A LOW CONTENT OF AMMONIA | L'OREAL (FR) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012038538-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE QUATERNARY AMMONIUM ESTER AND AT LEAST ONE SOLUBLE SALT OF DIVALENT METALS, AND PROCESS USING THE SAID COMPOSITION | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060034792-A1 | Cosmetic composition based on a cationic surfactant, an amino silicone or vinyl silicone, a fatty alcohol and a propellant | PHOSPHO1, SGMS1, SGMS2 | FAAH 473/4885CES1 2863/4885CES2 1877/4885 |
| US-20130340783-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR ZINC SALT AND AN AMINO SILICONE | KRT18, CUTA, PRDM7 | FAAH 4805/4885CES1 4332/4885CES2 3777/4885 |
| US-20130298934-A1 | DYE COMPOSITION HAVING A LOW CONTENT OF AMMONIA | KRT18, OAT, NUP205 | FAAH 500/4885CES1 3127/4885CES2 3006/4885 |
| US-20140053345-A1 | DYEING OR LIGHTENING PROCESS USING A COMPOSITION RICH IN FATTY SUBSTANCES COMPRISING AN ALCOHOL HAVING AT LEAST 20 CARBONS, COMPOSITIONS AND DEVICE | KRT18, ADH1C, ADH1A | FAAH 439/4885CES1 57/4885CES2 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.