Hydrochloric Acid

Hydrochloric Acid

SCHEMBL28875

CCCCCCCCCCCCCCCC(=O)C(C)(C(=O)CCCCCCCCCCCCCCC)N(C)C.Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG known ✓ P37231 5/20 0.45
HDAC11 known ✓ Q96DB2 4/20 0.45
ESR1 known ✓ P03372 1/20 0.45
PDE4A known ✓ P27815 1/20 0.45
PDE3A known ✓ Q14432 1/20 0.45
FAAH O00519 8/20 0.53
CES1 P23141 8/20 0.53
CES2 O00748 5/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
HSD17B10 Q99714 2/20 0.53
CYP1A2 P05177 1/20 0.53
PPARD Q03181 5/20 0.45
PPARA Q07869 5/20 0.45
TSHR P16473 3/20 0.45
GPR84 Q9NQS5 3/20 0.45
ALDH1A1 P00352 2/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2556207 1.00 FAAH (0.53) FAAHCES1CES2MEN1KMT2A
SCHEMBL5533296 0.98 FAAH (0.55) FAAHCES1CES2MEN1KMT2A
SCHEMBL540827 0.98 FAAH (0.55) FAAHCES1CES2MEN1KMT2A
Hydrochloric Acid SCHEMBL6565479 0.90 FAAH (0.61) FAAHCES1MEN1KMT2AHSD17B10
Hydrochloric Acid SCHEMBL6565477 0.90 FAAH (0.61) FAAHCES1MEN1KMT2AHSD17B10
SCHEMBL28766942 0.89 FAAH (0.50) FAAHCES1CES2MEN1KMT2A
SCHEMBL532715 0.88 FAAH (0.63) FAAHCES1MEN1KMT2AHSD17B10
SCHEMBL532713 0.88 FAAH (0.63) FAAHCES1MEN1KMT2AHSD17B10
SCHEMBL27899377 0.87 FAAH (0.48) FAAHCES1CES2MEN1KMT2A
SCHEMBL28532297 0.85 FAAH (0.43) FAAHCES1CES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12076432-B2 Method of repairing oxidatively treated hair CONOPCO, INC. (US) 2024-09-03 US claimed
CN-114599334-A Stable low pH personal care compositions and methods therefor 高露洁-棕榄公司 2022-06-07 CN claimed
US-9295859-B2 Porous, dissolvable solid substrate and surface resident coating comprising matrix microspheres THE PROCTER & GAMBLE COMPANY (US) 2016-03-29 US claimed
EP-1725298-B1 HAIR CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2007-05-02 EP claimed
US-20070081965-A1 Hair conditioning compositions CONOPCO, INC., D/B/A UNILEVER 2007-04-12 US claimed
EP-1725298-A1 HAIR CONDITIONING COMPOSITIONS Unilever Plc (GB) 2006-11-29 EP claimed
WO-2005048961-A1 HAIR CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2005-06-02 WO claimed
JP-8337969-A None JP disclosed
US-12624319-B2 Water disintegrable, foam producing article for use as a toilet bowl cleaner THE PROCTER & GAMBLE COMPANY (US) 2026-05-12 US disclosed
US-20250344929-A1 Fibrous Structures Comprising Particles and Methods for Making Same PROCTER & GAMBLE (US) 2025-11-13 US disclosed
EP-4197598-B1 ACTIVE AGENT-CONTAINING ARTICLES THAT EXHIBIT CONSUMER ACCEPTABLE ARTICLE IN-USE PROPERTIES PROCTER & GAMBLE (US) 2025-10-22 EP disclosed
US-12440083-B2 Fibrous structures comprising particles and methods for making same THE PROCTER & GAMBLE COMPANY (US) 2025-10-14 US disclosed
US-12433834-B2 Hair conditioning composition CONOPCO, INC. (US) 2025-10-07 US disclosed
US-20070081965-A1 Hair conditioning compositions CONOPCO, INC., D/B/A UNILEVER 2007-04-12 US disclosed
EP-1725298-A1 HAIR CONDITIONING COMPOSITIONS Unilever Plc (GB) 2006-11-29 EP disclosed
WO-2005048961-A1 HAIR CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2005-06-02 WO disclosed
US-6210660-B1 ILEX RESIN IS MADE BY A METHOD COMPRISING EXTRACTING LEAVES OF ILEX AQUIFOLIUM OR ILEX PARAGUARIENSIS WITH A SEMIPOLAR OR APOLAR, WATER-FREE ORGANIC SOLVENT, EITHER CONTINUOUSLY OR IN SUCCESSIVE MULTIPLE EXTRACTION STEPS. WELLA AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6117436-A CONDITIONER AND EMULSIFIER WITH CATIONIC OR ANIONIC BASE; HAIR, SKIN WELLA AKTIENGESELLSCHAFT (DE) 2000-09-12 US disclosed
US-5958395-A SMOOTHING OF THE HAIR SURFACE TO INCREASE LUSTER, GLOSS AND COLOR DEPTH BY APPLYING A HAIR CONDITIONER CONTAINING HOLLY (ILEX) LEAF RESIN OBTAINED BY HOT-EXTRACTION, HOT-FILTRATION, MIXING WITH FULLER'S EARTH; COSMETICS; SKIN PROTECTIVE FILMS WELLA AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed
JP-H08337969-A WATER-CONTAINING SOFTENING AND RINSING AGENT FOR TREATING FIBER PRODUCT WELLA AG 1996-12-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12440083-B2 Fibrous structures comprising particles and methods for making same FGB, CD68, SDCBP PPARG 3780/4885HDAC11 3419/4885ESR1 4601/4885
US-12624319-B2 Water disintegrable, foam producing article for use as a toilet bowl cleaner SI, SMS, SMURF1 PPARG 2247/4885HDAC11 2514/4885ESR1 4151/4885
US-20250344929-A1 Fibrous Structures Comprising Particles and Methods for Making Same FGB, CD68, SDCBP PPARG 3780/4885HDAC11 3419/4885ESR1 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.