SCHEMBL8739876

SCHEMBL8739876

CC(C)(C)c1ccc2c3ccc(C(C)(C)C)cc3n(-c3cccc(-n4c5cc(C(C)(C)C)ccc5c5ccc(C(C)(C)C)cc54)c3)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
KIF11 P52732 5/20 0.40
OPRD1 P41143 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
MAT2A P31153 1/20 0.36
OPRM1 P35372 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13132834 0.93 L3MBTL1 (0.48) NOTUMKIF11OPRD1L3MBTL1KDM4E
SCHEMBL14138105 0.89 L3MBTL1 (0.50) NOTUMKIF11L3MBTL1KDM4EATM
SCHEMBL25207777 0.89 MAT2A (0.42) NOTUMKDM4EMAT2AALDH1A1HPGD
SCHEMBL25708814 0.89 KDM4E (0.47) NOTUMKIF11OPRD1L3MBTL1KDM4E
SCHEMBL31003064 0.89 MAT2A (0.42) NOTUMKDM4EMAT2AALDH1A1HPGD
SCHEMBL26140551 0.89 KIF11 (0.46) NOTUMKIF11OPRD1MAT2AOPRM1
SCHEMBL13132926 0.88 KDM4E (0.36) NOTUMKIF11OPRD1L3MBTL1KDM4E
SCHEMBL63688 0.87 NOTUM (0.42) NOTUMKIF11OPRD1L3MBTL1KDM4E
SCHEMBL31297416 0.87 NOTUM (0.42) NOTUMKIF11OPRD1L3MBTL1KDM4E
SCHEMBL13132923 0.87 NOTUM (0.34) NOTUMKIF11OPRD1MAT2AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
WO-2011025068-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100244676-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100244676-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 NOTUM 4570/4885KIF11 3639/4885OPRD1 824/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 NOTUM 137/4885KIF11 4027/4885OPRD1 2021/4885
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE L1CAM, EED, CCNE2 NOTUM 4484/4885KIF11 2375/4885OPRD1 959/4885
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device VCL, L1CAM, EML4 NOTUM 1278/4885KIF11 86/4885OPRD1 2409/4885
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device VCL, L1CAM, EML4 NOTUM 1278/4885KIF11 86/4885OPRD1 2409/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 NOTUM 1278/4885KIF11 86/4885OPRD1 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.