Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921658 | 0.82 | LMNA (0.36) | TSHR | |
| SCHEMBL8744987 | 0.82 | GPR55 (0.39) | — | |
| SCHEMBL6601303 | 0.70 | AHR (0.50) | — | |
| Hydrochloric Acid SCHEMBL8764857 | 0.68 | MMP12 (0.34) | TSHR | |
| SCHEMBL7487283 | 0.68 | CYP3A4 (0.51) | — | |
| SCHEMBL24509831 | 0.68 | TSHR (0.48) | TSHR | |
| SCHEMBL6336282 | 0.67 | GPR55 (0.43) | — | |
| SCHEMBL8763953 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL8763946 | 0.67 | ALOX15 (0.35) | — | |
| SCHEMBL1003323 | 0.66 | ALOX5 (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537517-B1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |