SCHEMBL87477

SCHEMBL87477

O=S(=O)(O)c1c(O)ccc(-c2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.45
ALOX5 P09917 2/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
BCL2L1 Q07817 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PELI1 Q96FA3 1/20 0.38
DAPK1 P53355 2/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
MAOA P21397 2/20 0.36
KMT2A Q03164 2/20 0.36
PTGS2 P35354 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30633654 1.00 BACE1 (0.45) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL28020176 0.87 HDAC4 (0.46) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL4163081 0.87 BACE1 (0.43) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL29700247 0.85 ALDH1A1 (0.54) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL3042569 0.85 ALDH1A1 (0.54) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL28614880 0.82 TSHR (0.41) BACE1ALOX5ALDH1A1HPGDHSD17B10
Formaldehyde SCHEMBL5123936 0.81 ALDH1A1 (0.50) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL21794264 0.79 TSHR (0.46) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL3185678 0.79 PTGS2 (0.39) BCL2L1SMN1; SMN2TSHRMEN1MAPT
SCHEMBL21794267 0.78 TSHR (0.41) BACE1ALOX5ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020068665-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2020-04-02 WO claimed
EP-2916814-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN Colabs International Corporation (US) 2015-09-16 EP claimed
WO-2014074555-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN CoLabs International Corporation (US) 2014-05-15 WO claimed
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen CoLabs International Corporation (US) 2014-05-08 US claimed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP claimed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US claimed
WO-2010067327-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA (FR) 2010-06-17 WO claimed
WO-2010044076-A2 COSMETIC AND TOPICAL USE OF XANTHOHUMOL INCLUDING BRIGHTENING SKIN COMPLEXION AND REDUCING CUTANEOUS REDNESS SEDERMA (FR) 2010-04-22 WO claimed
EP-1924254-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION Biomas Ltd. (IL) 2008-05-28 EP claimed
WO-2007032010-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION BIOMAS LTD. (IL) 2007-03-22 WO claimed
US-20060193789-A1 Surfacant, film forming agent, water, gas propellant; plant and animal extracts and oils; may include malathion FOAMIX LTD. (IL) 2006-08-31 US claimed
EP-1495103-A4 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION SALVONA LLC (US) 2006-03-22 EP claimed
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2005-08-25 US claimed
US-6897281-B2 Breathable polyurethanes, blends, and articles NOVEON IP HOLDINGS CORP. (US) 2005-05-24 US claimed
EP-1495103-A1 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION Salvona L.L.C. (US) 2005-01-12 EP claimed
WO-2003087287-A1 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION SALVONA L.L.C. (US) 2003-10-23 WO claimed
US-20030195133-A1 Targeted controlled delivery compositions activated by changes in pH or salt concentration SALVONA L.L.C. 2003-10-16 US claimed
US-5837697-A CONTAINING SALICYLIC ACID, SUNSCREEN AGENT AND A CARRIER THE PROCTER & GAMBLE COMPANY (US) 1998-11-17 US claimed
US-11957769-B2 Polyhydroxy fullerene sunscreen active agents and compositions THE CLEVELAND CLINIC FOUNDATION (US) 2024-04-16 US disclosed
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 BACE1 2648/4885ALOX5 3715/4885ALDH1A1 2904/4885
US-20030195133-A1 Targeted controlled delivery compositions activated by changes in pH or salt concentration TRPC5, TRPV1, TRPV2 BACE1 812/4885ALOX5 1690/4885ALDH1A1 2305/4885
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen MSH6, TYR, CUTA BACE1 1198/4885ALOX5 856/4885ALDH1A1 854/4885
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 BACE1 2648/4885ALOX5 3715/4885ALDH1A1 2904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.