SCHEMBL8748843

SCHEMBL8748843

O=[C]C12CC3CC(C1)C(C3)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465574 0.86 GRIN2D (0.38)
SCHEMBL7517207 0.80
SCHEMBL692515 0.70 LMNA (0.30)
SCHEMBL1821165 0.65
SCHEMBL21376486 0.64
SCHEMBL11089627 0.62 THRB (0.42)
SCHEMBL12378023 0.62 HSD11B1 (0.34)
SCHEMBL328811 0.62 HSD11B1 (0.32)
SCHEMBL11091802 0.62 PKM (0.47)
SCHEMBL11088099 0.62 DPP4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599928-B1 STABILIZED COMPLEX LIGANDS AND THEIR USE IN LIQUID CRYSTAL DISPLAYS HOECHST AG (DE) 1997-03-19 EP disclosed
US-5445762-A Stabilized complex ligands and their use in liquid crystal displays HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0599928-A1 STABILIZED COMPLEX LIGANDS AND THEIR USE IN LIQUID CRYSTAL DISPLAYS. HOECHST AG (DE) 1994-06-08 EP disclosed
WO-1993004142-A1 STABILIZED COMPLEX LIGANDS AND THEIR USE IN LIQUID CRYSTAL DISPLAYS HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-04 WO disclosed
EP-0528415-A1 Stabilized complex ligands and their use in liquid crystal displays HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-24 EP disclosed