Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407228 | 0.70 | KCNA4 (0.36) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL8766756 | 0.69 | MAOA (0.48) | SLC6A2MAOAMAOBKDM1AMC4R | |
| SCHEMBL11475593 | 0.63 | KMT2A (0.44) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL7867641 | 0.60 | MC4R (0.49) | MEN1KMT2AMC4RGBA1 | |
| Hydrochloric Acid SCHEMBL48897 | 0.59 | SLC6A4 (0.41) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL7650165 | 0.59 | KIF11 (0.38) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL11400588 | 0.58 | CYP2D6 (0.38) | MEN1LMNACYP2D6HRH1SCN1A | |
| Diphenylmethane SCHEMBL7400899 | 0.56 | CALM1 (0.57) | LMNAHRH1SLC6A2MC4RGBA1 | |
| SCHEMBL1742163 | 0.56 | GBA1 (0.63) | SLC6A2MC4RGBA1 | |
| SCHEMBL25329264 | 0.56 | CYP2B6 (0.42) | MEN1LMNACYP2D6HRH1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298629-A | Intermediates in the synthesis of quinoline antibiotics | PFIZER INC. (US) | 1994-03-29 | — | — | US | disclosed |