SCHEMBL8767375

SCHEMBL8767375

O=C(NSc1ccc2ccccc2c1)Nc1ccc(C(=O)NS(=O)(=O)c2ccccc2O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
DEGS1 O15121 1/20 0.42
GPR27 Q9NS67 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
POLB P06746 1/20 0.40
NPC1 O15118 6/20 0.40
RAB9A P51151 6/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
KAT6A Q92794 2/20 0.38
ENPP1 P22413 2/20 0.38
ENPP2 Q13822 2/20 0.38
ENPP3 O14638 1/20 0.38
PTGES O14684 1/20 0.38
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776171 0.88 PTGES (0.44) CA2CA12CA1CA9POLB
SCHEMBL7776309 0.86 LMNA (0.42) CA2CA12CA1CA9POLB
SCHEMBL8768272 0.86 GPR27 (0.51) CA2DEGS1GPR27POLBNPC1
SCHEMBL8768060 0.85 KAT6A (0.51) CA2DEGS1GPR27POLBMAPT
SCHEMBL8767632 0.82 LMNA (0.51) CA2GPR27CA12CA1CA9
SCHEMBL8768261 0.81 HSD17B10 (0.54) GPR27POLBNPC1RAB9AMEN1
SCHEMBL8767411 0.80 FLT1 (0.51) CA2GPR27CA12CA1CA9
SCHEMBL7776174 0.79 SIRT1 (0.54) CA2CA12CA1CA9POLB
SCHEMBL6295396 0.74 KMT2A (0.50) CA2CA1CA9MAPTMEN1
SCHEMBL7774533 0.73 L3MBTL1 (0.47) CA2DEGS1CA1CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed