Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768766 | 0.81 | ACHE (0.45) | ACHEBCHEMTNR1AMTNR1BMETAP1 | |
| SCHEMBL8768044 | 0.80 | METAP1 (0.45) | ACHEBCHEMTNR1AMTNR1BMETAP1 | |
| SCHEMBL8767407 | 0.74 | TSHR (0.41) | ACHEBCHEMTNR1AMTNR1BTSHR | |
| SCHEMBL8768151 | 0.74 | DRD2 (0.52) | ACHEMTNR1AMTNR1BOPRM1 | |
| SCHEMBL5359275 | 0.67 | TSHR (0.46) | TSHRMEN1MAPTKMT2AOPRM1 | |
| SCHEMBL5582351 | 0.66 | CYP19A1 (0.77) | ACHEMETAP1CYP24A1 | |
| SCHEMBL16082195 | 0.66 | METAP1 (0.53) | ACHEMETAP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL5370790 | 0.65 | KMT2A (0.48) | TSHRMEN1POLBMAPTKMT2A | |
| SCHEMBL11860908 | 0.65 | ACHE (0.46) | ACHEBCHEMETAP1MEN1KMT2A | |
| SCHEMBL28019674 | 0.64 | CCR5 (0.47) | MTNR1AKMT2AOPRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |