Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767407 | 0.82 | TSHR (0.41) | ACHEBCHETSHRMTNR1AMTNR1B | |
| SCHEMBL8768766 | 0.81 | ACHE (0.45) | METAP1ACHEBCHEALDH1A1CYP19A1 | |
| SCHEMBL8767508 | 0.80 | ACHE (0.46) | METAP1ACHEBCHECYP24A1TSHR | |
| SCHEMBL8768151 | 0.74 | DRD2 (0.52) | ACHECYP19A1DRD2SIGMAR1MTNR1A | |
| SCHEMBL5582351 | 0.70 | CYP19A1 (0.77) | METAP1ACHECYP24A1CYP19A1CYP26A1 | |
| SCHEMBL4623145 | 0.68 | CYP24A1 (0.66) | METAP1ACHEBCHECYP24A1CYP19A1 | |
| SCHEMBL11826337 | 0.67 | ACHE (0.43) | ACHEBCHECYP24A1CYP19A1TSHR | |
| SCHEMBL691404 | 0.67 | SLC6A2 (0.52) | HTR2A | |
| SCHEMBL5359275 | 0.67 | TSHR (0.46) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6272399 | 0.67 | METAP1 (0.65) | METAP1ACHECYP24A1CYP19A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0579833-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018461-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |