SCHEMBL87679

SCHEMBL87679

OB(O)c1cccc2[nH]ncc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.55
NOS1 P29475 4/20 0.53
AXL P30530 2/20 0.53
METAP2 P50579 1/20 0.49
ROCK2 O75116 2/20 0.48
ROCK1 Q13464 2/20 0.48
JAK2 O60674 1/20 0.46
JAK1 P23458 1/20 0.46
BRD4 O60885 1/20 0.42
DHPS P49366 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CDK2 P24941 1/20 0.41
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370496 1.00 IDO1 (0.55) IDO1NOS1AXLMETAP2ROCK2
Hydrochloric Acid SCHEMBL632116 0.98 IDO1 (0.53) IDO1NOS1AXLMETAP2ROCK2
Hydrochloric Acid SCHEMBL29954979 0.98 IDO1 (0.53) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL8784 0.77 IDO1 (0.41) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL31178789 0.76 IDO1 (0.56) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL15288440 0.76 ROCK1 (0.41) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL29951352 0.76 ROCK1 (0.41) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL29955211 0.76 IDO1 (0.56) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL29956165 0.74 IDO1 (0.35) IDO1NOS1AXLMETAP2ROCK2
SCHEMBL21636438 0.74 METAP2 (0.53) IDO1METAP2NPC1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495769-B2 Inorganic light emitting diode and inorganic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2022-11-08 US claimed
US-20210167321-A1 INORGANIC LIGHT EMITTING DIODE AND INORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-06-03 US claimed
US-9980668-B2 Photoluminescent nanostructure-based sensors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-05-29 US claimed
EP-2739977-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS Massachusetts Institute of Technology (US) 2014-06-11 EP claimed
US-20130035567-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS NATIONAL SCIENCE FOUNDATION 2013-02-07 US claimed
WO-2013019722-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
US-12570607-B2 Compound as cyclin-dependent kinase 9 inhibitor and use thereof CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2026-03-10 US disclosed
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI PHARMACEUTICAL CO LTD (JP) 2026-03-05 US disclosed
US-20260049074-A1 THIADIAZOLYL DERIVATIVES IDEAYA BIOSCIENCES, INC. (US) 2026-02-19 US disclosed
EP-4688788-A1 PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS Pfizer Inc. (US) 2026-02-11 EP disclosed
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) 2026-01-15 US disclosed
US-12516059-B2 Pyrazolopyridine compounds and uses thereof INCYTE CORPORATION (US) 2026-01-06 US disclosed
US-7342115-B2 Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology NEUROGEN CORPORATION (US) 2008-03-11 US disclosed
EP-1745033-A2 4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES NEUROGEN CORPORATION (US) 2007-01-24 EP disclosed
US-20050277654-A1 4,5-Disubstituted-2-aryl pyrimidines NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2005-12-15 US disclosed
WO-2005110416-A2 4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES NEUROGEN CORPORATION (US) 2005-11-24 WO disclosed
EP-1565452-A2 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS NEUROGEN CORPORATION (US) 2005-08-24 EP disclosed
US-20040158067-A1 3-substituted-6-aryl pyridines NEUROGEN CORPORATION 2004-08-12 US disclosed
WO-2004043925-A2 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS NEUROGEN CORPORATION (US) 2004-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049074-A1 THIADIAZOLYL DERIVATIVES POLH, POLM, POLD1 IDO1 3942/4885NOS1 4767/4885AXL 4394/4885
US-20050277654-A1 4,5-Disubstituted-2-aryl pyrimidines C5AR2, C3AR1, C5AR1 IDO1 349/4885NOS1 2770/4885AXL 464/4885
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 IDO1 4446/4885NOS1 2727/4885AXL 4415/4885
US-12570607-B2 Compound as cyclin-dependent kinase 9 inhibitor and use thereof CDK9, CDK4, CDKL4 IDO1 3551/4885NOS1 3832/4885AXL 1256/4885
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY MYT1, NTMT1, MYL6 IDO1 950/4885NOS1 1797/4885AXL 3835/4885
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF WRN, MSH2, MSH6 IDO1 2631/4885NOS1 4535/4885AXL 4741/4885
US-20040158067-A1 3-substituted-6-aryl pyridines C3AR1, C5AR1, C5AR2 IDO1 253/4885NOS1 2585/4885AXL 595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.