Sugi Predict

Sugi Predict / Compounds / SCHEMBL8773642

SCHEMBL8773642

SCHEMBL8773642

CCc1ccc(OCCCO)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.58
▸ ALDH1A1 P00352 3/20 0.58
▸ SMN1; SMN2 Q16637 3/20 0.58
▸ MAPT P10636 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ HRH3 Q9Y5N1 2/20 0.50
▸ USP2 O75604 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ CASP1 P29466 1/20 0.50
▸ SLCO1B3 Q9NPD5 1/20 0.50
▸ SLCO1B1 Q9Y6L6 1/20 0.50
▸ NR1I2 O75469 1/20 0.48
▸ RXRA P19793 1/20 0.47
▸ RXRB P28702 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1377082 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL26122857 0.92 HRH3 (0.55) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL301362 0.89 NR1I2 (0.60) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL17445912 0.87 ALDH1A1 (0.66) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL8298166 0.85 LTA4H (0.61) LMNAALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL17445914 0.85 HRH3 (0.64) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL95824 0.85 SMN1; SMN2 (0.63) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL5929490 0.84 MAPT (0.62) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL555384 0.84 ALDH1A1 (0.56) ALDH1A1HRH3NR1I2CYP2D6
SCHEMBL4667887 0.84 ALDH1A1 (0.59) LMNAALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1262583-C Process for preparing stabilized polyester CIBA SPECIALLY CHEMICALS HOLDI (CH) 2006-07-05 — — CN claimed
CN-1529730-A Process for preparing stabilized polyesters �������⻯ѧƷ�ع����޹�˾ 2004-09-15 — — CN claimed
US-20160096978-A1 COMPOSITION FOR FORMING A COATING TYPE BPSG FILM, SUBSTRATE, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-07 — — US disclosed
US-20160064220-A1 METHOD FOR PRODUCING SEMICONDUCTOR APPARATUS SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-03-03 — — US disclosed
US-20150004791-A1 COMPOSITION FOR FORMING A COATING TYPE BPSG FILM, SUBSTRATE FORMED A FILM BY SAID COMPOSITION, AND PATTERNING PROCESS USING SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-01 — — US disclosed
US-8778970-B2 Benzyl piperidine compound DAINIPPON SUMITOMO PHARMA CO., LTD (JP) 2014-07-15 — — US disclosed
US-20130303786-A1 BENZYLPIPERIZINE COMPOUND DAINIPPON SUMITOMO PHARMA CO (JP) 2013-11-14 — — US disclosed
US-8557998-B2 Benzylpiperizine compound DAINIPPON SUMITOMO PHARMA CO., LTD (JP) 2013-10-15 — — US disclosed
US-20120259122-A1 BENZYLPIPERIZINE COMPOUND DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-10-11 — — US disclosed
US-8232405-B2 Benzylpiperizine compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-07-31 — — US disclosed
US-20120130077-A1 BENZYL PIPERIDINE COMPOUND DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-05-24 — — US disclosed
US-20090124624-A1 SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF SANOFI-AVENTIS (FR) 2009-05-14 — — US disclosed
US-20090124624-A1 SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF SANOFI-AVENTIS (FR) 2009-05-14 — — US disclosed
EP-1829876-A1 NITROGENEOUS TRICYCLIC COMPOUND Asahi Kasei Pharma Corporation (JP) 2007-09-05 — — EP disclosed
US-7235543-B2 Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof SCHERING CORPORATION (US) 2007-06-26 — — US disclosed
WO-2007042668-A1 DERIVATIVES OF 1-AMINO-ISOQUINOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS IN THE TREATMENT OF A DYSFUNCTION ASSOCIATED WITH MCH RECEPTOR 1 SANOFI-AVENTIS (FR) 2007-04-19 — — WO disclosed
WO-2007042660-A2 SUBSTITUTED 1-AMINO-PHTHALZINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2007-04-19 — — WO disclosed
WO-2007042669-A2 DERIVATIVES OF 4-AMINO-QUINAZOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFIS-AVENTIS (FR) 2007-04-19 — — WO disclosed
CN-1262583-C Process for preparing stabilized polyester CIBA SPECIALLY CHEMICALS HOLDI (CH) 2006-07-05 — — CN disclosed
CN-1529730-A Process for preparing stabilized polyesters �������⻯ѧƷ�ع����޹�˾ 2004-09-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130077-A1 BENZYL PIPERIDINE COMPOUND HTR1D, HTR1A, HTR1B LMNA 4675/4885ALDH1A1 1160/4885SMN1; SMN2 2842/4885
US-20130303786-A1 BENZYLPIPERIZINE COMPOUND OPRM1, GRM1, CHRM1 LMNA 3893/4885ALDH1A1 1260/4885SMN1; SMN2 2789/4885
US-20120259122-A1 BENZYLPIPERIZINE COMPOUND OPRM1, GRM1, CHRM1 LMNA 3893/4885ALDH1A1 1260/4885SMN1; SMN2 2789/4885
US-20090124624-A1 SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF AGTR1, AGTR2, AHR LMNA 2114/4885ALDH1A1 60/4885SMN1; SMN2 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.