Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CDC25C | P30307 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774796 | 0.96 | NQO1 (0.41) | NQO1KDM4ELMNAALDH1A1GPR84 | |
| SCHEMBL8774925 | 0.90 | CYP2D6 (0.46) | RAB9AMAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL8774847 | 0.90 | ACACB (0.43) | RAB9AMAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL8774330 | 0.87 | CYP3A4 (0.43) | RAB9AMAPTL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8775001 | 0.85 | PKM (0.42) | LMNAALDH1A1SMN1; SMN2CHRNA7 | |
| SCHEMBL8774833 | 0.85 | LMNA (0.44) | RAB9AMAPTL3MBTL1NPC1LMNA | |
| SCHEMBL8774513 | 0.84 | TAAR1 (0.39) | RAB9AL3MBTL1NPC1LMNAGPR84 | |
| SCHEMBL8774334 | 0.84 | NPC1 (0.40) | RAB9AMAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8774813 | 0.83 | MEN1 (0.42) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9155765 | 0.82 | RAB9A (0.40) | RAB9AMAPTL3MBTL1NQO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |