Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774796 | 0.85 | NQO1 (0.41) | MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL8774833 | 0.82 | LMNA (0.44) | RAB9AMAPTL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL8775001 | 0.82 | PKM (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8775165 | 0.82 | TAAR1 (0.42) | TAAR1RAB9AL3MBTL1NPC1HTT | |
| SCHEMBL8774829 | 0.82 | RAB9A (0.36) | RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL8774157 | 0.81 | RAB9A (0.39) | RAB9AMAPTL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL9155931 | 0.79 | TAAR1 (0.44) | TAAR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8774498 | 0.79 | HTR2A (0.40) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL8774925 | 0.79 | CYP2D6 (0.46) | RAB9AMAPTL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL8774847 | 0.79 | ACACB (0.43) | RAB9AMAPTL3MBTL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |