Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774683 | 0.89 | RAB9A (0.40) | ALDH1A1NPSR1MAPTNPC1RAB9A | |
| SCHEMBL8774663 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1TDP1L3MBTL1MAPTNPC1 | |
| SCHEMBL8774662 | 0.85 | RAB9A (0.46) | ALDH1A1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL8272903 | 0.85 | ALDH1A1 (0.44) | ALDH1A1NPSR1TDP1L3MBTL1MAPT | |
| SCHEMBL8774190 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1MAPTGPR84 | |
| SCHEMBL8774078 | 0.81 | LMNA (0.47) | ALDH1A1NPSR1L3MBTL1MAPTNPC1 | |
| SCHEMBL8774856 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL10282386 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPSR1NPC1RAB9ALMNA | |
| SCHEMBL8774425 | 0.79 | RAB9A (0.46) | ALDH1A1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL8774839 | 0.79 | EGLN1 (0.45) | ALDH1A1NPSR1TDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |