Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282386 | 0.93 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL8774663 | 0.90 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL8774499 | 0.89 | TAAR1 (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1NPSR1 | |
| SCHEMBL8774662 | 0.88 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1TP53HSD17B10 | |
| SCHEMBL8774078 | 0.84 | LMNA (0.47) | RAB9ASMN1; SMN2NPC1HSD17B10ALDH1A1 | |
| SCHEMBL8774856 | 0.84 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2NPC1PKMHSD17B10 | |
| SCHEMBL8774190 | 0.83 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL8774882 | 0.83 | RAB9A (0.41) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL8774425 | 0.82 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1TP53HSD17B10 | |
| SCHEMBL12430744 | 0.81 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |