Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099590 | 0.92 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1LMNAMAPK13 | |
| SCHEMBL8094759 | 0.91 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1LMNAMAPK13 | |
| SCHEMBL8095856 | 0.90 | ALDH1A1 (0.43) | PTGS2PTGS1ALDH1A1LMNACNR1 | |
| SCHEMBL8100548 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1LMNACNR1 | |
| SCHEMBL8776749 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1ALDH1A1LMNARORC | |
| SCHEMBL8420124 | 0.76 | ALDH1A1 (0.39) | PTGS2PTGS1ALDH1A1LMNANPSR1 | |
| SCHEMBL8776720 | 0.76 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2L3MBTL1 | |
| SCHEMBL8776825 | 0.76 | PTGS2 (0.46) | PTGS2PTGS1ALDH1A1RORCCNR1 | |
| SCHEMBL8420193 | 0.76 | MCL1 (0.39) | PTGS2PTGS1ALDH1A1LMNANPSR1 | |
| SCHEMBL8101431 | 0.75 | PTGS2 (0.56) | PTGS2PTGS1CNR1CNR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |