Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779100 | 0.89 | LNPEP (0.42) | ACACBLNPEPPDE4DPDE4APDE4B | |
| SCHEMBL8779428 | 0.85 | IRAK4 (0.43) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8779243 | 0.84 | PPARG (0.38) | ACACBLNPEPIRAK4 | |
| SCHEMBL8779254 | 0.83 | ACACB (0.38) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8882835 | 0.83 | PDE4D (0.39) | ACACBLNPEPPDE4DPDE4APDE4B | |
| SCHEMBL8779264 | 0.82 | AAK1 (0.35) | — | |
| SCHEMBL8779267 | 0.81 | ALDH1A1 (0.36) | KMOIRAK4 | |
| SCHEMBL8779308 | 0.81 | ALDH1A1 (0.36) | KMOIRAK4 | |
| SCHEMBL8779176 | 0.80 | HPGD (0.38) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8779212 | 0.80 | HPGD (0.38) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |