Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780750 | 0.93 | TDP1 (0.37) | TDP1MCHR1KCNH2PKMPLA2G7 | |
| SCHEMBL8780751 | 0.85 | PKM (0.51) | KCNH2PKMSMN1; SMN2HPGDLTA4H | |
| SCHEMBL8780867 | 0.85 | KCNH2 (0.43) | TDP1MCHR1KCNH2PKMADORA3 | |
| SCHEMBL8780940 | 0.83 | ADORA2A (0.43) | MCHR1KCNH2PKMADORA3ADORA2A | |
| SCHEMBL8780815 | 0.82 | ADORA2A (0.38) | MCHR1KCNH2PKMALDH1A1ADORA3 | |
| SCHEMBL8780990 | 0.81 | KCNH2 (0.39) | MCHR1KCNH2PKMADORA3ADORA2A | |
| SCHEMBL8780857 | 0.81 | ALDH1A1 (0.34) | KCNH2PKMPLA2G7ALDH1A1RXFP1 | |
| SCHEMBL8780727 | 0.80 | L3MBTL1 (0.44) | PKMALDH1A1POLBKDM4EMAPT | |
| SCHEMBL8780907 | 0.79 | PKM (0.52) | TDP1KCNH2PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL8780789 | 0.79 | ADORA2A (0.41) | MCHR1KCNH2PKMADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |