Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 9/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796818 | 0.89 | KDM4E (0.33) | HTR6NAMPTPTGS2 | |
| SCHEMBL8799009 | 0.85 | CYP11B1 (0.43) | NAMPTLMNA | |
| SCHEMBL9087771 | 0.85 | HTR6 (0.42) | HTR6NAMPTPTGS2CYP2C9BACE1 | |
| SCHEMBL8796821 | 0.83 | HTR6 (0.33) | HTR6NAMPTPTGS2 | |
| SCHEMBL9067938 | 0.82 | CYP19A1 (0.41) | PTGS2 | |
| SCHEMBL9086171 | 0.81 | KCNH2 (0.42) | PTGS2BACE1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL8797782 | 0.79 | CYP11B2 (0.40) | BACE1KCNH2 | |
| SCHEMBL8796991 | 0.77 | POLB (0.40) | KCNH2 | |
| SCHEMBL8798430 | 0.75 | IMPDH2 (0.43) | HTR6CYP2C9LMNACYP1A2PKM | |
| SCHEMBL9088314 | 0.73 | RARA (0.39) | HTR6NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514942-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1997-03-05 | — | — | EP | disclosed |
| US-5493029-A | USEFUL IN TREATING ASTHMA AND HYPERTENSION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-02-20 | — | — | US | disclosed |
| US-5300511-A | Spiro-benzopyran derivatives and useful for treating asthma and hypertension | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-04-05 | — | — | US | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |