Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428506 | 0.82 | ALDH1A1 (0.50) | MTNR1AMTNR1BMEN1GAAKMT2A | |
| SCHEMBL7528860 | 0.79 | MTNR1A (0.62) | IDO1MTNR1AMTNR1BMEN1GAA | |
| SCHEMBL8801039 | 0.77 | LTA4H (0.39) | GAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8633540 | 0.77 | IDO1 (0.46) | IDO1PTPRBNPSR1MEN1GAA | |
| SCHEMBL8329540 | 0.76 | IDO1 (0.50) | IDO1PTPRBNPSR1MEN1KMT2A | |
| SCHEMBL8803281 | 0.75 | HDAC3 (0.51) | IDO1PTPRBNPSR1CA1CA2 | |
| SCHEMBL8799056 | 0.74 | SIGMAR1 (0.51) | IDO1PTPRBNPSR1CA1CA2 | |
| SCHEMBL31298914 | 0.73 | HPGD (0.55) | IDO1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8633439 | 0.73 | NPSR1 (0.46) | IDO1PTPRBNPSR1CA12CA1 | |
| SCHEMBL24187607 | 0.72 | TDP1 (0.59) | NPSR1MEN1GAAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |