Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801039 | 0.77 | LTA4H (0.39) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8633548 | 0.75 | SLC7A5 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8803294 | 0.74 | MMP8 (0.38) | ALDH1A1SMN1; SMN2MMP8 | |
| SCHEMBL8329548 | 0.74 | LTA4H (0.41) | ALDH1A1MAPTPOLBLMNATSHR | |
| SCHEMBL8799066 | 0.73 | LMNA (0.39) | SMN1; SMN2LMNAMMP8 | |
| SCHEMBL5428506 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12470718 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7516437 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8633153 | 0.71 | CYP1A2 (0.33) | POLBCYP1A2CYP2C19MMP8 | |
| SCHEMBL7445938 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |