Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800127 | 0.86 | ALDH1A1 (0.41) | CRHBPCRHR2L3MBTL1LMNAPOLB | |
| SCHEMBL8799550 | 0.84 | ALDH1A1 (0.38) | L3MBTL1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8800075 | 0.84 | ITGB1 (0.39) | L3MBTL1LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8800451 | 0.84 | TYK2 (0.42) | L3MBTL1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8800035 | 0.81 | GHSR (0.40) | CRHBPCRHR2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL7815641 | 0.79 | TDP1 (0.43) | CRHBPCRHR2TDP1L3MBTL1LMNA | |
| SCHEMBL8799385 | 0.77 | GHSR (0.38) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8801121 | 0.77 | GPR35 (0.39) | LMNAPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16583563 | 0.76 | TDP1 (0.60) | CRHBPCRHR2TDP1L3MBTL1LMNA | |
| SCHEMBL8799666 | 0.76 | GHSR (0.42) | L3MBTL1POLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |