SCHEMBL8815547

SCHEMBL8815547

Brc1ccc2c(c1)c1c3oc4ccccc4c3ccc1n2-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 3/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
POLB P06746 2/20 0.38
TSHR P16473 2/20 0.38
BRCA1 P38398 1/20 0.38
CA12 O43570 1/20 0.38
RXFP1 Q9HBX9 2/20 0.37
PPARG P37231 1/20 0.37
NR2E3 Q9Y5X4 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294117 0.92 CA9 (0.37) CA9L3MBTL1KDM4EATMALDH1A1
SCHEMBL23437393 0.90 L3MBTL1 (0.42) CA9L3MBTL1KDM4EATMALDH1A1
SCHEMBL16482283 0.87 ALOX5 (0.44) CA9ATMGABRPGABRDGABRA1
SCHEMBL16481911 0.87 GABRP (0.39) CA9L3MBTL1KDM4EATMALDH1A1
SCHEMBL15426630 0.87 KDM4E (0.41) CA9L3MBTL1KDM4EATMALDH1A1
SCHEMBL15335182 0.87 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1MEN1
SCHEMBL4554363 0.86 KDM4E (0.50) CA9L3MBTL1KDM4EATMALDH1A1
SCHEMBL15490877 0.86 GABRP (0.36) L3MBTL1KDM4EATMALDH1A1MEN1
SCHEMBL16171139 0.86 KDM4E (0.44) L3MBTL1KDM4EATMALDH1A1MEN1
SCHEMBL16482124 0.86 KDM4E (0.47) CA9L3MBTL1KDM4EATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same SFC CO., LTD. (KR) 2021-07-27 US disclosed
US-20180029983-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-02-01 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
WO-2017038728-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2017-03-09 WO disclosed
WO-2014057659-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed
US-20140077179-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-20 US disclosed
US-20140077179-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-20 US disclosed
WO-2012067425-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180029983-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE RER1, RCOR1, LEF1 CA9 1228/4885L3MBTL1 410/4885KDM4E 1864/4885
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same HARS1, ALDH1A2, NR2E3 CA9 3821/4885L3MBTL1 562/4885KDM4E 3813/4885
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A3 CA9 4013/4885L3MBTL1 451/4885KDM4E 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.