Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.47 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arsanilic Acid SCHEMBL1649934 | 0.88 | TSHR (0.62) | CYP2C19MAPTRAB9AMEN1KMT2A | |
| SCHEMBL3406380 | 0.82 | CYP2C19 (0.79) | CYP2C19MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1527750 | 0.82 | CYP2C19 (0.79) | CYP2C19MAPTRAB9AMEN1KMT2A | |
| SCHEMBL886903 | 0.81 | CYP2C19 (0.76) | CYP2C19MAPTRAB9AMEN1KMT2A | |
| SCHEMBL886901 | 0.81 | CYP2C19 (0.76) | CYP2C19MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11329226 | 0.72 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL16556 | 0.72 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11329248 | 0.72 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL205992 | 0.72 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11329238 | 0.72 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130196057-A1 | METHOD FOR PREPARING A SURFACE ENHANCED RAMAN SPECTROSCOPY PARTICLE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-08-01 | — | — | US | claimed |
| US-20110070662-A1 | RAMAN-ACTIVE REAGENTS AND THE USE THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-03-24 | — | — | US | claimed |
| US-20110070661-A1 | RAMAN-ACTIVE REAGENTS AND THE USE THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-03-24 | — | — | US | claimed |
| EP-2255175-A1 | MULTIPLEXED ANALYSIS METHODS USING SERS-ACTIVE NANOPARTICLES | Morpho Detection, Inc. (US) | 2010-12-01 | — | — | EP | claimed |
| US-7829348-B2 | Raman-active reagents and the use thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-11-09 | — | — | US | claimed |
| US-20100279272-A1 | MULTIPLEXED ANALYSIS METHODS USING SERS-ACTIVE NANOPARTICLES | GE HOMELAND PROTECTION, INC. | 2010-11-04 | — | — | US | claimed |
| US-7824926-B1 | Raman-active reagents and the use thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-11-02 | — | — | US | claimed |
| WO-2009102598-A1 | MULTIPLEXED ANALYSIS METHODS USING SERS-ACTIVE NANOPARTICLES | GENERAL ELECTRIC COMPANY (US) | 2009-08-20 | — | — | WO | claimed |
| US-20050089901-A1 | Raman-active reagents and the use thereof | NI, JING | 2005-04-28 | — | — | US | claimed |
| US-10968474-B2 | Devices for detecting target biological molecules from cells and viruses | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190323069-A1 | DEVICES FOR DETECTING TARGET BIOLOGICAL MOLECULES FROM CELLS AND VIRUSES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2019-10-24 | — | — | US | disclosed |
| US-10301667-B2 | Devices for detecting target biological molecules from cells and viruses | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-10088478-B2 | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-10-02 | — | — | US | disclosed |
| US-9823246-B2 | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-11-21 | — | — | US | disclosed |
| US-20030211488-A1 | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection | NORTHWESTERN UNIVERSITY (US) | 2003-11-13 | — | — | US | disclosed |
| EP-0587008-B1 | Surface-enhanced raman spectroscopy immunoassy | ABBOTT LAB (US) | 1999-02-10 | — | — | EP | disclosed |
| US-5567628-A | Surface-enhanced raman spectroscopy immunoassay method, composition and kit | ABBOTT LABORATORIES (US) | 1996-10-22 | — | — | US | disclosed |
| US-5445972-A | Raman label and its conjugate in a ligand-binding assay for a test sample analyte | ABBOTT LABORATORIES (US) | 1995-08-29 | — | — | US | disclosed |
| US-5376556-A | Surface-enhanced Raman spectroscopy immunoassay | ABBOTT LABORATORIES (US) | 1994-12-27 | — | — | US | disclosed |
| US-5266498-A | Ligand binding assay for an analyte using surface-enhanced scattering (SERS) signal | ABBOTT LABORATORIES (US) | 1993-11-30 | — | — | US | disclosed |