Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873492 | 0.88 | PGK1 (0.40) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL8874141 | 0.83 | NUDT1 (0.51) | AURKAPDPK1TGFBR1AURKBNUDT1 | |
| SCHEMBL8873225 | 0.82 | LMNA (0.37) | PGK1CYP2C19KDM4ELMNACYP1A2 | |
| SCHEMBL8874243 | 0.80 | RAB9A (0.48) | NUDT1CYP2C19ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7935910 | 0.79 | HSP90AA1 (0.35) | NUDT1CYP2C19ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20161606 | 0.78 | RAB9A (0.44) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL7804829 | 0.74 | NPC1 (0.44) | AURKAPDPK1TGFBR1AURKBNUDT1 | |
| SCHEMBL8874168 | 0.73 | KMT2A (0.41) | NUDT1CYP2C19ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7796331 | 0.73 | KMT2A (0.43) | NUDT1CYP2C19SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL7934010 | 0.73 | KMT2A (0.49) | CYP2C19CYP2D6ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591694-A | COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0446743-B1 | Herbicidal sulfonylureas, process for their preparation and intermediates | BASF AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0656004-A1 | DUAL FUNCTIONAL ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE AGENTS | CYTOMED, INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0600967-B1 | HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME | BASF AG (DE) | 1995-04-19 | — | — | EP | disclosed |
| EP-0600967-A1 | HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME. | BASF AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| US-5276007-A | Herbicidal sulfonylureas | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| WO-1993005048-A2 | HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-18 | — | — | WO | disclosed |
| EP-0446743-A2 | Herbicidal sulfonylureas, process for their preparation and intermediates | BASF Aktiengesellschaft (DE) | 1991-09-18 | — | — | EP | disclosed |