Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474832 | 0.84 | LAP3 (0.36) | LAP3MAPTMMP1MMP2MMP3 | |
| SCHEMBL13804308 | 0.84 | PGK1 (0.45) | LPAR3LPAR1LPAR2PGK1PGK2 | |
| SCHEMBL2471542 | 0.84 | PGK1 (0.45) | LPAR3LPAR1LPAR2PGK1PGK2 | |
| SCHEMBL28452952 | 0.81 | CYP3A4 (0.33) | MAPTCYP3A4L3MBTL1 | |
| SCHEMBL28389815 | 0.80 | LAP3 (0.33) | LAP3MAPTMMP1MMP2MMP3 | |
| SCHEMBL12146353 | 0.80 | LAP3 (0.39) | LAP3MAPTMMP1MMP2MMP3 | |
| SCHEMBL12342799 | 0.78 | PPARD (0.38) | LAP3MAPTMMP1MMP2MMP3 | |
| SCHEMBL15783767 | 0.78 | PLA2G2A (0.43) | LAP3MAPTMMP1MMP2MMP3 | |
| SCHEMBL4761816 | 0.78 | — | — | |
| SCHEMBL6858014 | 0.78 | CYP3A4 (0.48) | MAPTCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8052992-B2 | Lipid preparation including glycerophospholid esters with polyunsaturated fatty acid (PUFA); increased bioavailability of PUFA; use as pharmaceutical, nutraceutical e.g. neurodegenerative disorders | ENZYMOTEC LTD. (IL) | 2011-11-08 | — | — | US | disclosed |
| US-20090074857-A1 | Glycerophospholipids for the improvement of cognitive functions | ENZYMOTEC LTD. | 2009-03-19 | — | — | US | disclosed |
| US-20080226757-A1 | Use of a Ginkgo Complexes for the Enhancement of Cognitive Functions and the Alleviation of Mental Fatigue | INDENA S.P.A. (IT) | 2008-09-18 | — | — | US | disclosed |
| US-20070293449-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF DOUBLE-STRANDED RNA | NASTECH PHARMACEUTICAL COMPANY INC. (US) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226757-A1 | Use of a Ginkgo Complexes for the Enhancement of Cognitive Functions and the Alleviation of Mental Fatigue | PHOSPHO1, PSEN1, PLCB3 | SAT1 4563/4885LAP3 3397/4885MAPT 381/4885 |
| US-20090074857-A1 | Glycerophospholipids for the improvement of cognitive functions | ELOVL6, PLA2G4C, PLA2G2A | SAT1 1942/4885LAP3 265/4885MAPT 505/4885 |
| US-20070293449-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF DOUBLE-STRANDED RNA | ADAR, POLRMT, MTREX | SAT1 2735/4885LAP3 2203/4885MAPT 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.